Changing the Course in Type One Diabetes 2025 Resource Hub –
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Day-of Conference Reports
Conference Highlights
- NIH welcomes hundreds of researchers, lauding the impact of collaboration in science
- Research advances improve diabetes management, but T1D cure remains elusive
- Restoring alpha cell glucagon secretion in T1D via paracrine inhibition with serotonin and somatostatin
- Complexity of T1D necessitates collective, interdisciplinary approach
- Microphysiological systems as a way to explore the complex immunopathogenesis of T1D
- Up-regulation of HLA-B offers unique insight into T1D pathogenesis, with potential as an effective biomarker of disease progression
- DYRK1A inhibitor harmine and GLP-1 RA exendin-4 in combination show synergistic effect in beta cell regeneration and potential for T1D reversal
- Quick Take: Prof. Anette-Gabriele Ziegler on determinants of islet autoimmunity, primary prevention trials, and screening for T1D
- Dr. William Cefalu on the importance of aligning the Human Islet Research Network’s research efforts with the NIDDK’s priorities
- The search for disease-specific biomarkers: How RNA sequencing can aid in a better understanding of T1D pathogenesis
- Paving the way for stem cell-derived islet therapy: How synthetic suppression of T cells may establish localized immune suppression
- Gene variants and T1D susceptibility: Induction of stress in beta cells as a key factor in disease progression
- Pancreatic maturity at time of T1D onset impacts disease heterogeneity
- Engineering islet-antigen specific and long-lived regulatory T cells for T1D
- Multiome profiling and AI-assisted data analysis to better understand genetic expression underlying T1D